Peptides

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What are Peptides?

Peptides are organic chemical compounds that are the basic building blocks of organisms. The chemical compounds consist of amino acids linked by peptide bonds. Peptides are essential for basic physiological and biochemical processes. Peptides are elements that occur naturally in human skin. Peptide compounds can have various amounts of amino acids, depending on the type of peptide. Among others, collagen, which impacts skin health, consists of three polypeptide chains.

The use of peptides is vast; the compounds are used in therapy or cosmetics. The bioactivity of amino acid chains discovered by scientists has meant that these chemical compounds are also used in the pharmaceutical industry. Peptides are obtained by various means; they can be obtained from natural, plant, or animal sources or produced synthetically. Let's find out more about peptides and how they affect your health.

Peptides: What Are, Functions, Uses and Safety

Functions

Peptides are elements that have many functions in the human body. Large chains of amino acids linked together from many peptides are called proteins. Where peptides form fewer links, on the other hand, they are called peptide bonds. Small chains of chemical compounds are involved in biological processes that involve many complex mechanisms. The functions that amino acid chains perform in the human body include:

Regulation of the Immune System

Peptides are involved in the regulation of the immune response. This means that they influence the process of protecting the body from harmful agents. The innate immune response is the human body's defense mechanism. Peptides modulate and stimulate the immune system to act and fight harmful agents. It allows amino acid chains to alleviate inflammation and promote regeneration.

Peptides can, therefore, combat viruses, fungi, and bacteria that are dangerous to the body. They also stimulate different areas of the body, which impacts the overall immune system. Peptides that influence the immune system to a high level are cytokines. Cytokines are peptide hormone-like substances mainly produced by cells of the immune system.

Antibiotic Properties

Antibiotic amino acid chains also have additional defense functions, such as protecting the body by destroying pathogenic microorganisms. As such, amino acid chains are natural antibiotics. The antibiotic properties of peptides make these compounds used to produce drugs and antimicrobial substances with diverse structures and mechanisms of action.

In addition to it, peptides have many more valuable properties. Some amino acid chains affect cytokine release, making them angiogenic. In the case of cancer, peptides can inhibit the proliferation or migration of tumor cells and the formation of tumor blood vessels.

Peptides: What Are, Functions, Uses and Safety

Structural Properties

Peptides are known for their influence on tissue construction and repair. It is, therefore, of great use in cosmetology and dermatology. Proteins are the basic building blocks of the skin and other organs, and peptides stimulate skin cells to produce its main building proteins. Biomimetic amino acid chains stimulate cells to regenerative processes, slowing aging. By stimulating repair processes, peptide compounds influence the production and synthesis of collagenTrusted Source and elastinTrusted Source. It is essential for preserving the skin's youthful appearance, elasticity, and resilience.

Amino acid chains can also indirectly protect against free radicals. It is necessary to know that the amount of amino acid chains produced naturally in the body decreases with age. Therefore, products containing peptides can be followed to benefit from their valuable properties.

Endocrine Functions

Some amino acid chain compounds are hormones that influence various processes in the body. C-peptide is produced in an equal ratio to insulinTrusted Source. Testing C-peptide levels is mainly used to monitor pancreatic function and assess insulin production, which can be crucial in diagnosing and treating diabetes.

Another hormonal peptide is glucagonTrusted Source. The compound is a polypeptide made up of amino acids. Glucagon also has effects on various organs and systems. The primary function of this peptide is to regulate the concentration of glucose, free fatty acids, and amino acids in the blood. The determination of glucagon levels in the blood is used in the diagnosis of diabetes mellitus and other disorders of glucose metabolism, as well as in the diagnosis of diseases of the gastrointestinal tract, thyroid, and adrenal glands.

Neurotransmission

Further functions of peptides include the transmission of signals between neurons. As such, some peptides are neurotransmitters. It includes neuropeptidesTrusted Source, which transmit information in the nervous system. Neuropeptides are protein molecules that interact with different neurotransmitters to regulate the nature of the neuronal response. Peptide neurotransmitters are chemical molecules that enable the brain to function correctly.

A type of such neurotransmitter is neuropeptide Y, which is produced by neurons and affects neurotransmission in the peripheral and central nervous system. Neuropeptide Y has many vital functions, including controlling bodily processes. The peptide influences circadian rhythm, memory, and emotional aspects. In addition, neuropeptide Y controls blood vessel contractions, blood pressure, intestinal peristalsis, and much more.

Peptides: What Are, Functions, Uses and Safety

Opioid Effects

Drugs that are used to control pain can also be peptide-bound. When the drug is taken, the peptides bind to the receptors, triggering a signal that reduces pain in the patient. In addition to pain control, peptides can also have a stress-reducing effect. Opioid peptides are usually in the type of hormones or neurotransmitters.

Nutrient Absorption

Peptides in foods can also improve the body's absorption of various elements. These are the additional functions of peptides supplied to the body from outside. Research results indicate that peptides contained in products have a beneficial effect on calciumTrusted Source absorption. Amino acid binding can prevent diseases such as tooth decay and osteoporosis.

Uses

Peptides are produced naturally in the human body and perform many useful functions. In addition, peptides have many additional health uses due to their properties. They are trendy in the cosmetic industry, as their action affects the skin's condition. In addition, the chemical compounds are used for many different purposes. Find out about the use of peptide chains in various fields.

Cosmetic Industry

Cosmetics with peptides are available in various types. The amino acid compounds act on the skin through several mechanisms. Primarily, they stimulate collagen and elastin production, making the skin more elastic and resistant to damage. Peptides on the face and body influence the skin's regenerative processes, accelerating wound healing and reducing inflammation. Thanks to these properties, regular use of cosmetics with peptides causes a visible improvement in skin condition. Peptide compounds also carry different active ingredients in cosmetics, improving their absorption and effectiveness. Creams with peptides in a variety of formulations are top-rated.

Peptides: What Are, Functions, Uses and Safety

Neuropeptides are also used in the cosmetic industry. Peptides help relax the muscles and make the skin look smooth and relaxed. The substances stimulate and irritate the club by paralyzing the nerve endings responsible for muscle contraction. This allows the compounds to act similarly to Botox, inhibiting the transmission of signals. Cosmetics with peptides are, therefore, worth using when the skin needs nourishment and regeneration. The products also work well for getting rid of wrinkles and eliminating signs of skin aging.

Medical Industry

Some peptides are used in the production of medicines. Consequently, these chemicals are also used in medicine and for therapeutic purposes. There are many peptide drugs with a wide range of effects. Peptide compounds can act as growth factors, neurotransmitters, hormones, and anti-infective agents. Peptide drugs are used for various types of problems and diseases. Peptides work well for viral and bacterial infections.

In addition, peptide-based medicines work well for cardiovascular issues, osteoporosis, and endocrine disorders. Alternative peptide therapies are also used to treat cancer. The most popular peptide drug is insulin, used to treat diabetes. The effects of peptides on the skin also make them useful for skin diseases such as atopic dermatitis. Peptides play an essential role in wound healing and inhibition of inflammation.

Imaging Studies

Amino acid chains also have essential uses in cancer diagnosis. Substances can act as imaging probes to help detect tumors. Molecular imagingTrusted Source belongs to biomedical techniques that allow the analysis of intracellular phenomena occurring in living organisms and lead to an understanding of their physiological processes. This diagnostic method can also be beneficial in cancer diagnosis. In some cases, tumors are challenging to detect with standard imaging methods. Sometimes, healthy and cancerous cells look identical under the microscope. However, in detecting cancer, a quick diagnosis is crucial for the survival of patients. Molecular imaging using peptides also works well for monitoring the area during tumor excision surgery.

Peptides: What Are, Functions, Uses and Safety

Food Industry

Peptides are also present in the foods we eat. Eating proteins that have peptides can have a beneficial effect on health. Foods enriched with amino acid chain compounds are functional foods with antioxidants. As such, eating peptide-enriched food can protect against various infections and diseases. In addition, the food's peptides affect blood pressure regulation. Amino acid chains in foods can also benefit the lipid profile and have antimicrobial and cytotoxic effects. Bioactive peptides are mainly found in mushrooms, meat, and plant products with high protein content. Active amino acid chains can also be found in dairy products such as yogurt and cow's milkTrusted Source. Due to their broad spectrum of effects, manufacturers readily use bioactive peptides to enrich foods.

Safety

Peptides are chemical compounds with many health benefits. People benefit from the properties of peptides in various ways. Amino acid chains can be added to cosmetics on the skin and hair. In addition to it, peptides are used to produce medicines. Humans can also consume peptide compounds in food or supplements. However, is the use of peptides completely safe? Some sources report possible dangers of side effects from using cosmetics, peptide-enriched foods, supplements, and medicines.

Supplements and Foods

Everybody selling peptide products has had to pass a safety check. In general, experts reassure that bioactive peptides extracted from food are harmless. However, beware of the toxicity of such products and never exceed the doses indicated on the packaging. If you want to start taking peptide supplements, we advise you to consult your doctor first. Peptides are very safe molecules that do not show cytotoxicity or allergenicity in studies, but caution should always be exercised.

Peptides: What Are, Functions, Uses and Safety

Cosmetics

Cosmetics enriched with peptides are also considered relatively safe. However, some sources report that excessive use of peptide cosmetics may cause mild side effects. Some peptide cosmetics can cause eye irritationTrusted Source, so care should be taken when applying such products to the face. Too high concentrations of peptide compounds in cosmetics can also lead to irritation and sensitization. However, during the control of cosmetic products, the amounts of compounds used are tested, creating combinations that show safety for the general population.

Drugs

Peptide drugs show less safety, as some of the medicines can cause side effects. Among others, ACE inhibitorsTrusted Source used for heart disease can cause many symptoms during therapy. One characteristic symptom is coughing. In addition, side effects of these drugs include taste changes, swelling, and eczema. Other peptide drugs can also cause various symptoms, especially with long-term use. Antibiotic peptide drugs can also make bacteria and other pathogens resistant to this therapy. You are also advised to follow your doctor's instructions when taking the medication.

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Summary

Peptides are essential organic chemical compounds for the human body as basic building blocks. The chemical compounds consist of amino acids linked together by bonds. Peptides are crucial for basic physiological and biochemical processes, such as immune response regulation. In addition, peptides protect the body against pathogens and have regenerative properties. Many of the peptides also have functions as hormones and neurotransmitters.

Peptides are widespread and used in therapy and cosmetics. Peptide drugs, for example, are used for heart disease. These chemical compounds are added to many creams and cosmetics to achieve the desired properties. Peptides can be derived from natural plant/animal sources or produced synthetically. As such, peptides can also be delivered to the body through food or supplements. In general, peptides are considered to be safe chemical compounds.

Sources

August 15, 2024
10 minutes read
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